Stockholm University
Browse

Supplementary Fig. 2d | FUS localization in genome-edited iPSC lines

dataset
posted on 2025-04-25, 07:49 authored by Christoph SchweingruberChristoph Schweingruber, Jonas MechtersheimerJonas Mechtersheimer, Marc-David Ruepp

This item is part of the Figshare Project:
Early mitochondrial dysfunction revealed across FUS- and TARDBP-ALS at single cell resolution


From Data Availability Statement for the forthcoming paper in Nature Communications entitled:

Single-cell RNA sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS

"We have deposited all raw and processed RNA sequencing data generated in this study on the NCBI Gene Expression Omnibus (GEO) under the accession number GSE226482. The C9orf72-ALS bulk RNA sequencing data was retrieved directly from the authors of the study.

[Items under this Figshare Project contain:] "Scans of fluorescent western blots, raw imaging files from confocal microscopy, the analysis files from Opera Phenix, qPCR data sets, and Seahorse assay result files."

--------------------------------------------

[Item specific description:]

FUS localization in genome-edited iPSC lines

These files are immunofluorescent stainings of FUS localization in genome-edited iPSC-lines

The microscopy file format is ND2 which can be opened with the free standalone program the NIS-Elements Viewer (Nikon). More information about the software and file format can be found here: https://www.microscope.healthcare.nikon.com/products/software/nis-elements/software-resources


History

Associated Publication

Single-cell RNA sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS. (forthcoming in: Nature Communications)

Affiliation (institution of first SU-affiliated author)

  • 431 Institutionen för biokemi och biofysik (DBB) | Department of Biochemistry and Biophysics (DBB)

access_level

  • public

access_condition

  • PUBLIC

Usage metrics

    Stockholm University

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC