Supplementary Fig. 2d | FUS localization in genome-edited iPSC lines
This item is part of the Figshare Project:
Early mitochondrial dysfunction revealed across FUS- and TARDBP-ALS at single cell resolution
From Data Availability Statement for the forthcoming paper in Nature Communications entitled:
Single-cell RNA sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS
"We have deposited all raw and processed RNA sequencing data generated in this study on the NCBI Gene Expression Omnibus (GEO) under the accession number GSE226482. The C9orf72-ALS bulk RNA sequencing data was retrieved directly from the authors of the study.
[Items under this Figshare Project contain:] "Scans of fluorescent western blots, raw imaging files from confocal microscopy, the analysis files from Opera Phenix, qPCR data sets, and Seahorse assay result files."
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[Item specific description:]
FUS localization in genome-edited iPSC lines
These files are immunofluorescent stainings of FUS localization in genome-edited iPSC-lines
The microscopy file format is ND2 which can be opened with the free standalone program the NIS-Elements Viewer (Nikon). More information about the software and file format can be found here: https://www.microscope.healthcare.nikon.com/products/software/nis-elements/software-resources
History
Associated Publication
Schweingruber, C., Nijssen, J., Mechtersheimer, J. et al. (2025): Single-cell RNA-sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS. Nat Commun 16, 4633. https://doi.org/10.1038/s41467-025-59679-1Affiliation (institution of first SU-affiliated author)
- 431 Institutionen för biokemi och biofysik (DBB) | Department of Biochemistry and Biophysics (DBB)
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